Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 3 | MCP-1 (MCAF) | 4046.0 | 66 | |
| RA2159 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 3 | MCP-1 (MCAF) | 1485.0 | 85 | |
| N2586 | IL-17A | 100 | ng/mL | 3 | MCP-1 (MCAF) | 8758.0 | 89 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7866.0 | 86 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7090.0 | 85 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 3 | MCP-1 (MCAF) | 9514.5 | 70 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 3 | MCP-1 (MCAF) | 6684.0 | 71 | |
| N2586 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 3 | MCP-1 (MCAF) | 4263.0 | 60 | |
| RA2159 | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 2522.5 | 66 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 2125.0 | 87 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 2287.0 | 63 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 2842.0 | 85 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 2610.0 | 67 | |
| RA2159 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 1190.0 | 83 | |
| RA2159 | Sigma A6730 | 3.0 | uM | 3 | MCP-1 (MCAF) | 3185.5 | 84 | ||||
| N2586 | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 7172.0 | 81 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 7502.0 | 79 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 5993.0 | 93 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 7206.0 | 68 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 5219.0 | 73 | |
| N2586 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 3 | MCP-1 (MCAF) | 3107.0 | 70 | |
| N2586 | Sigma A6730 | 3.0 | uM | 3 | MCP-1 (MCAF) | 5929.0 | 65 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 12859.0 | 89 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 11461.5 | 78 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 11743.5 | 78 |