Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Ruxolitinib | 0.3 | uM | 1 | MCP-1 (MCAF) | 6079.0 | 70 | ||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | MCP-1 (MCAF) | 6275.0 | 74 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | MCP-1 (MCAF) | 4398.0 | 49 | ||||
| N2586 | 1 | MCP-1 (MCAF) | 6729.0 | 36 | |||||||
| 0 | MCP-1 (MCAF) | 45.0 | 83 | ||||||||
| 0 | MCP-1 (MCAF) | 68.0 | 57 | ||||||||
| RA2159 | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 14222.5 | 56 | ||||
| RA2159 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 13167.0 | 77 | |
| RA2159 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 13736.5 | 64 | |
| RA2159 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 12103.0 | 94 | |
| RA2159 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 14271.0 | 84 | |
| RA2159 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 6302.5 | 72 | |
| RA2159 | EO1428 | 1.0 | uM | 1 | MCP-1 (MCAF) | 3231.0 | 61 | ||||
| N2586 | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 14759.0 | 79 | ||||
| N2586 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 14834.0 | 67 | |
| N2586 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 15730.0 | 78 | |
| N2586 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 15189.5 | 72 | |
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 14697.0 | 69 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 13960.5 | 70 | |
| N2586 | EO1428 | 1.0 | uM | 1 | MCP-1 (MCAF) | 7449.0 | 43 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 13567.0 | 87 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 11491.0 | 79 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 10176.0 | 74 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 13853.5 | 76 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 14634.0 | 83 |