Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-13 | 35.5 | 62 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL-13 | 41.0 | 83 | |
| N2586 | Leptin | 1 | ng/mL | 3 | IL-13 | 44.5 | 72 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL-13 | 48.0 | 57 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-13 | 42.0 | 65 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-13 | 55.0 | 58 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-13 | 47.0 | 52 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL-13 | 54.0 | 60 | |
| RA2159 | Adiponectin | 5 | ng/mL | 3 | IL-13 | 37.0 | 69 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL-13 | 41.0 | 76 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-13 | 38.5 | 70 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-13 | 30.0 | 43 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-13 | 34.5 | 70 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL-13 | 42.0 | 59 | |
| N2586 | Adiponectin | 5 | ng/mL | 3 | IL-13 | 54.0 | 65 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL-13 | 56.0 | 57 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-13 | 45.0 | 65 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-13 | 38.0 | 65 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-13 | 53.5 | 50 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL-13 | 53.0 | 51 | |
| RA2159 | IGF-I | 100 | ug/mL | 3 | IL-13 | 35.5 | 68 | ||||
| RA2159 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 3 | IL-13 | 39.0 | 79 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-13 | 39.0 | 67 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-13 | 49.0 | 64 | |
| RA2159 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-13 | 45.5 | 60 |