Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA2159 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-1B | 17.0 | 75 | |
RA2159 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-1B | 16.0 | 71 | |
RA2159 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 3 | IL-1B | 16.0 | 67 | |
RA2159 | Sigma A6730 | 3.0 | uM | 3 | IL-1B | 14.0 | 69 | ||||
N2586 | IL-6 | 100 | ug/mL | 3 | IL-1B | 21.0 | 79 | ||||
N2586 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 3 | IL-1B | 15.0 | 62 | |
N2586 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-1B | 12.5 | 68 | |
N2586 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-1B | 14.0 | 69 | |
N2586 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-1B | 15.0 | 54 | |
N2586 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 3 | IL-1B | 35.0 | 67 | |
N2586 | Sigma A6730 | 3.0 | uM | 3 | IL-1B | 9.5 | 58 | ||||
RA2159 | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 29.5 | 58 | ||||
RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 22.5 | 70 | |
RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 18.0 | 53 | |
RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 26.0 | 72 | |
RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 25.0 | 50 | |
RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 14.0 | 70 | |
RA2159 | PI103 | 0.1 | uM | 3 | IL-1B | 15.5 | 40 | ||||
N2586 | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 32.5 | 72 | ||||
N2586 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 27.0 | 68 | |
N2586 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 28.5 | 56 | |
N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 30.5 | 52 | |
N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 15.0 | 57 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-1B | 29.0 | 53 | |
N2586 | PI103 | 0.1 | uM | 3 | IL-1B | 13.0 | 87 |