Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 27.0 52
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 19.0 77
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 19.0 83
N2586 PI103 0.1
uM
 3
CTACK
 15.0 68
0
CTACK
 18.0 60
RA2159 TNF-a 100
ng/mL
 3
CTACK
 20.0 53
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
CTACK
 17.5 56
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
CTACK
 19.0 75
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
CTACK
 17.0 40
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
CTACK
 15.0 50
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
CTACK
 17.0 69
RA2159 EO1428 1.0
uM
 3
CTACK
 14.0 44
N2586 TNF-a 100
ng/mL
 3
CTACK
 16.0 59
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
CTACK
 24.0 74
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
CTACK
 14.0 54
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
CTACK
 20.0 75
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
CTACK
 22.0 67
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
CTACK
 17.0 96
N2586 EO1428 1.0
uM
 3
CTACK
 34.0 61
0
CTACK
 19.0 61
RA2159 3
CTACK
 19.0 73
RA2159 PD184352 0.1
uM
 3
CTACK
 18.5 48
RA2159 Lestaurtinib 0.3
uM
 3
CTACK
 24.0 61
RA2159 Ruxolitinib 0.3
uM
 3
CTACK
 18.0 33
RA2159 Tofacitinib 0.3
uM
 3
CTACK
 13.0 59