Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | M-CSF | 189.0 | 46 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | M-CSF | 207.0 | 32 | |
| N2586 | 1 | M-CSF | 127.0 | 46 | |||||||
| RA2159 | Adiponectin | 5 | ng/mL | 1 | M-CSF | 128.5 | 50 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | M-CSF | 139.5 | 54 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | M-CSF | 142.0 | 61 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | M-CSF | 134.5 | 72 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | M-CSF | 168.0 | 57 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | M-CSF | 170.0 | 68 | |
| N2586 | Adiponectin | 5 | ng/mL | 1 | M-CSF | 167.0 | 75 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | M-CSF | 166.0 | 71 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | M-CSF | 156.0 | 49 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | M-CSF | 166.0 | 53 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | M-CSF | 214.0 | 57 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | M-CSF | 143.0 | 70 | |
| RA2159 | Leptin | 1 | ng/mL | 1 | M-CSF | 117.5 | 82 | ||||
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | M-CSF | 97.0 | 55 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | M-CSF | 91.0 | 63 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | M-CSF | 155.5 | 62 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | M-CSF | 126.0 | 49 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 1 | M-CSF | 121.5 | 40 | |
| N2586 | Leptin | 1 | ng/mL | 1 | M-CSF | 204.0 | 29 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | M-CSF | 203.0 | 75 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | M-CSF | 143.5 | 56 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | M-CSF | 211.0 | 33 |