Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
TRAIL
 126.0 71
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
TRAIL
 115.0 71
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
TRAIL
 103.0 51
N2586 EO1428 1.0
uM
 1
TRAIL
 38.0 71
RA2159 IL-1 alpha 100
ng/mL
 1
TRAIL
 46.5 50
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 44.0 75
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 52.5 62
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 43.5 52
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 40.0 57
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 33.0 53
RA2159 PI103 0.1
uM
 1
TRAIL
 27.0 71
N2586 IL-1 alpha 100
ng/mL
 1
TRAIL
 91.0 60
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 91.0 65
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 120.5 66
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 101.5 70
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 95.0 73
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
TRAIL
 69.0 49
N2586 PI103 0.1
uM
 1
TRAIL
 39.0 53
RA2159 IL-6 100
ug/mL
 1
TRAIL
 26.0 64
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 1
TRAIL
 26.5 62
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
TRAIL
 25.0 56
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
TRAIL
 28.0 67
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
TRAIL
 29.0 62
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 1
TRAIL
 25.0 46
RA2159 Sigma A6730 3.0
uM
 1
TRAIL
 28.0 78