Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 63.0 57
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 75.0 89
N2586 PI103 0.1
uM
 3
SCF
 49.0 73
0
SCF
 20.0 75
RA2159 TNF-a 100
ng/mL
 3
SCF
 198.5 66
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
SCF
 97.0 74
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 97.0 82
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 87.5 54
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 95.5 78
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
SCF
 53.0 75
RA2159 EO1428 1.0
uM
 3
SCF
 39.0 51
N2586 TNF-a 100
ng/mL
 3
SCF
 178.0 62
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
SCF
 181.5 86
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 180.5 62
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 185.0 84
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 81.0 52
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
SCF
 135.0 80
N2586 EO1428 1.0
uM
 3
SCF
 80.0 76
0
SCF
 17.0 51
RA2159 3
SCF
 39.0 81
RA2159 PD184352 0.1
uM
 3
SCF
 42.5 58
RA2159 Lestaurtinib 0.3
uM
 3
SCF
 44.0 60
RA2159 Ruxolitinib 0.3
uM
 3
SCF
 37.0 55
RA2159 Tofacitinib 0.3
uM
 3
SCF
 37.0 85
RA2159 IKK16 2.0
uM
 3
SCF
 39.0 43