Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL3
 43.0 81
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IL3
 33.0 65
N2586 IL-17A 100
ng/mL
 3
IL3
 51.0 62
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IL3
 44.0 86
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL3
 47.0 75
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL3
 125.0 77
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL3
 35.0 73
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IL3
 40.0 59
RA2159 IL-6 100
ug/mL
 3
IL3
 39.5 82
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IL3
 45.0 59
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IL3
 47.0 77
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL3
 39.0 88
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL3
 43.0 63
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
IL3
 45.0 55
RA2159 Sigma A6730 3.0
uM
 3
IL3
 48.0 83
N2586 IL-6 100
ug/mL
 3
IL3
 103.0 78
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IL3
 42.0 56
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IL3
 37.0 66
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL3
 41.0 61
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL3
 41.0 79
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
IL3
 36.0 63
N2586 Sigma A6730 3.0
uM
 3
IL3
 43.0 73
RA2159 IL-1 alpha 100
ng/mL
 3
IL3
 43.5 64
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
IL3
 52.5 74
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL3
 46.5 88