Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Ruxolitinib 0.3
uM
 1
IL3
 48.0 82
N2586 Tofacitinib 0.3
uM
 1
IL3
 49.0 61
N2586 IKK16 2.0
uM
 1
IL3
 40.0 50
N2586 1
IL3
 45.5 44
0
IL3
 57.0 67
0
IL3
 42.0 52
RA2159 TNF-a 100
ng/mL
 1
IL3
 41.0 59
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
IL3
 40.0 83
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 51.5 90
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 46.0 75
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 62.5 70
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL3
 41.5 64
RA2159 EO1428 1.0
uM
 1
IL3
 45.0 71
N2586 TNF-a 100
ng/mL
 1
IL3
 59.0 57
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
IL3
 52.0 47
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 46.5 42
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 46.0 75
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 52.5 80
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL3
 50.0 46
N2586 EO1428 1.0
uM
 1
IL3
 46.0 57
RA2159 IL-1 alpha 100
ng/mL
 1
IL3
 52.0 65
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 47.0 78
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 55.5 70
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 53.0 50
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 49.5 54