Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA2159 | Lestaurtinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL1-a | 48.0 | 55 | |
RA2159 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL1-a | 51.0 | 54 | |
RA2159 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL1-a | 58.0 | 43 | |
RA2159 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 1 | IL1-a | 65.0 | 43 | |
N2586 | Visfatin | 1 | ng/mL | 1 | IL1-a | 75.0 | 45 | ||||
N2586 | PD184352 | 0.1 | uM | Visfatin | 1 | ng/mL | 1 | IL1-a | 126.0 | 34 | |
N2586 | Lestaurtinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL1-a | 215.0 | 65 | |
N2586 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL1-a | 59.0 | 40 | |
N2586 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL1-a | 82.0 | 39 | |
N2586 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 1 | IL1-a | 50.5 | 28 | |
0 | IL1-a | 50.0 | 67 | ||||||||
RA2159 | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 69.5 | 44 | ||||
RA2159 | PD184352 | 0.1 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 79.0 | 50 | |
RA2159 | Lestaurtinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 50.0 | 48 | |
RA2159 | Ruxolitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 119.5 | 80 | |
RA2159 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 50.0 | 62 | |
RA2159 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 65.5 | 70 | |
N2586 | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 54.0 | 61 | ||||
N2586 | PD184352 | 0.1 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 47.0 | 35 | |
N2586 | Lestaurtinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 86.0 | 36 | |
N2586 | Ruxolitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 70.0 | 31 | |
N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 48.0 | 48 | |
N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL1-a | 65.5 | 30 | |
0 | IL1-a | 63.5 | 56 | ||||||||
RA2159 | 2 | IL1-a | 85.0 | 65 |