Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | HGF | 39.5 | 82 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | HGF | 35.5 | 64 | |
| N2586 | Leptin | 1 | ng/mL | 3 | HGF | 52.5 | 64 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | HGF | 57.5 | 84 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | HGF | 46.0 | 63 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | HGF | 49.5 | 60 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | HGF | 45.0 | 67 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | HGF | 50.0 | 54 | |
| RA2159 | Adiponectin | 5 | ng/mL | 3 | HGF | 73.0 | 57 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | HGF | 59.0 | 86 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | HGF | 48.0 | 60 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | HGF | 55.0 | 72 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | HGF | 55.0 | 53 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | HGF | 55.0 | 77 | |
| N2586 | Adiponectin | 5 | ng/mL | 3 | HGF | 78.0 | 59 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | HGF | 75.0 | 66 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | HGF | 67.0 | 61 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | HGF | 71.0 | 80 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | HGF | 70.0 | 45 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | HGF | 65.0 | 74 | |
| RA2159 | IGF-I | 100 | ug/mL | 3 | HGF | 58.5 | 82 | ||||
| RA2159 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 3 | HGF | 42.0 | 70 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | HGF | 35.0 | 63 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | HGF | 39.5 | 64 | |
| RA2159 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | HGF | 46.0 | 67 |