Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
b-NGF
 288.5 48
N2586 JNK-IN-11 0.3
uM
 TNF-a 100
ng/mL
 2
b-NGF
 289.0 39
N2586 PD184352 0.1
uM
 2
b-NGF
 115.0 59
RA2159 IL-1 alpha 100
ng/mL
 2
b-NGF
 147.0 67
RA2159 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 119.5 62
RA2159 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 129.5 62
RA2159 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 219.0 55
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 152.0 68
RA2159 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 113.5 54
RA2159 Lestaurtinib 0.3
uM
 2
b-NGF
 36.0 54
N2586 IL-1 alpha 100
ng/mL
 2
b-NGF
 346.0 59
N2586 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 301.0 51
N2586 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 310.5 46
N2586 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 439.5 62
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 354.5 48
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 273.0 45
N2586 Lestaurtinib 0.3
uM
 2
b-NGF
 82.0 57
RA2159 IL-6 100
ug/mL
 2
b-NGF
 52.0 66
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
b-NGF
 38.5 66
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 2
b-NGF
 46.5 50
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
b-NGF
 45.0 65
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
b-NGF
 38.0 53
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
b-NGF
 47.0 33
RA2159 Ruxolitinib 0.3
uM
 2
b-NGF
 53.0 51
N2586 IL-6 100
ug/mL
 2
b-NGF
 109.0 55