Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | b-NGF | 38.0 | 53 | |
| RA2159 | 1 | b-NGF | 35.0 | 56 | |||||||
| N2586 | IGF-I | 100 | ug/mL | 1 | b-NGF | 103.0 | 47 | ||||
| N2586 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 1 | b-NGF | 95.0 | 76 | |
| N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | b-NGF | 64.5 | 30 | |
| N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | b-NGF | 82.5 | 56 | |
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | b-NGF | 87.5 | 40 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | b-NGF | 77.5 | 38 | |
| N2586 | 1 | b-NGF | 71.0 | 35 | |||||||
| RA2159 | Adiponectin | 5 | ng/mL | 1 | b-NGF | 94.0 | 61 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | b-NGF | 97.0 | 63 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | b-NGF | 101.5 | 72 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | b-NGF | 99.5 | 64 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | b-NGF | 131.0 | 63 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | b-NGF | 117.0 | 78 | |
| N2586 | Adiponectin | 5 | ng/mL | 1 | b-NGF | 132.5 | 52 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | b-NGF | 113.0 | 54 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | b-NGF | 106.0 | 51 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | b-NGF | 114.0 | 41 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | b-NGF | 122.0 | 47 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | b-NGF | 96.0 | 59 | |
| RA2159 | Leptin | 1 | ng/mL | 1 | b-NGF | 41.0 | 52 | ||||
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | b-NGF | 37.0 | 55 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | b-NGF | 29.0 | 50 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | b-NGF | 44.5 | 62 |