Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL18 | 21.0 | 61 | |
| N2586 | Leptin | 1 | ng/mL | 3 | IL18 | 58.0 | 71 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL18 | 62.0 | 94 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL18 | 51.0 | 71 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL18 | 62.5 | 82 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL18 | 43.0 | 97 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL18 | 52.0 | 70 | |
| RA2159 | Adiponectin | 5 | ng/mL | 3 | IL18 | 66.0 | 65 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL18 | 57.0 | 83 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL18 | 64.0 | 81 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL18 | 67.5 | 88 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL18 | 60.5 | 58 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL18 | 58.0 | 86 | |
| N2586 | Adiponectin | 5 | ng/mL | 3 | IL18 | 107.0 | 86 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL18 | 111.5 | 74 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL18 | 95.5 | 62 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL18 | 106.0 | 61 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL18 | 93.0 | 55 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL18 | 101.0 | 83 | |
| RA2159 | IGF-I | 100 | ug/mL | 3 | IL18 | 15.0 | 90 | ||||
| RA2159 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 3 | IL18 | 19.0 | 79 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL18 | 16.0 | 64 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL18 | 18.0 | 81 | |
| RA2159 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL18 | 21.0 | 66 | |
| RA2159 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 3 | IL18 | 19.0 | 74 |