Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 PD184352 0.1
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 77.0 45
N2586 Lestaurtinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 68.0 53
N2586 Ruxolitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 84.5 40
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 79.0 55
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL18
 73.0 37
0
IL18
 13.0 67
RA2159 2
IL18
 20.0 80
RA2159 EO1428 1.0
uM
 2
IL18
 20.0 83
RA2159 PI103 0.1
uM
 2
IL18
 18.5 84
RA2159 Sigma A6730 3.0
uM
 2
IL18
 18.0 88
RA2159 JNK-IN-8 3.0
uM
 2
IL18
 21.0 83
RA2159 JNK-IN-11 0.3
uM
 2
IL18
 21.0 81
RA2159 2
IL18
 19.0 57
N2586 2
IL18
 48.5 74
N2586 EO1428 1.0
uM
 2
IL18
 50.5 66
N2586 PI103 0.1
uM
 2
IL18
 50.0 72
N2586 Sigma A6730 3.0
uM
 2
IL18
 58.5 64
N2586 JNK-IN-8 3.0
uM
 2
IL18
 46.0 76
N2586 JNK-IN-11 0.3
uM
 2
IL18
 42.5 48
N2586 2
IL18
 49.0 70
0
IL18
 14.0 85
0
IL18
 11.0 82
RA2159 TNF-a 100
ng/mL
 2
IL18
 79.5 80
RA2159 EO1428 1.0
uM
 TNF-a 100
ng/mL
 2
IL18
 67.0 65
RA2159 PI103 0.1
uM
 TNF-a 100
ng/mL
 2
IL18
 69.5 76