Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
IL18
78.0 86
RA2159 IKK16 2.0
uM
TNF-a 100
ng/mL
1
IL18
36.0 61
RA2159 EO1428 1.0
uM
1
IL18
18.5 76
N2586 TNF-a 100
ng/mL
1
IL18
248.5 56
N2586 PD184352 0.1
uM
TNF-a 100
ng/mL
1
IL18
215.5 58
N2586 Lestaurtinib 0.3
uM
TNF-a 100
ng/mL
1
IL18
194.5 60
N2586 Ruxolitinib 0.3
uM
TNF-a 100
ng/mL
1
IL18
230.5 64
N2586 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
IL18
241.0 71
N2586 IKK16 2.0
uM
TNF-a 100
ng/mL
1
IL18
222.0 35
N2586 EO1428 1.0
uM
1
IL18
54.0 81
RA2159 IL-1 alpha 100
ng/mL
1
IL18
42.0 76
RA2159 PD184352 0.1
uM
IL-1 alpha 100
ng/mL
1
IL18
41.5 88
RA2159 Lestaurtinib 0.3
uM
IL-1 alpha 100
ng/mL
1
IL18
58.0 61
RA2159 Ruxolitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
IL18
45.0 66
RA2159 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
IL18
41.5 56
RA2159 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
IL18
19.5 70
RA2159 PI103 0.1
uM
1
IL18
18.0 60
N2586 IL-1 alpha 100
ng/mL
1
IL18
136.0 66
N2586 PD184352 0.1
uM
IL-1 alpha 100
ng/mL
1
IL18
159.0 66
N2586 Lestaurtinib 0.3
uM
IL-1 alpha 100
ng/mL
1
IL18
214.0 59
N2586 Ruxolitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
IL18
186.0 56
N2586 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
IL18
175.0 81
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
IL18
90.0 56
N2586 PI103 0.1
uM
1
IL18
39.0 63
RA2159 IL-6 100
ug/mL
1
IL18
18.0 64