Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA2159 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL18 | 78.0 | 86 | |
RA2159 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL18 | 36.0 | 61 | |
RA2159 | EO1428 | 1.0 | uM | 1 | IL18 | 18.5 | 76 | ||||
N2586 | TNF-a | 100 | ng/mL | 1 | IL18 | 248.5 | 56 | ||||
N2586 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 1 | IL18 | 215.5 | 58 | |
N2586 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL18 | 194.5 | 60 | |
N2586 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL18 | 230.5 | 64 | |
N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL18 | 241.0 | 71 | |
N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL18 | 222.0 | 35 | |
N2586 | EO1428 | 1.0 | uM | 1 | IL18 | 54.0 | 81 | ||||
RA2159 | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 42.0 | 76 | ||||
RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 41.5 | 88 | |
RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 58.0 | 61 | |
RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 45.0 | 66 | |
RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 41.5 | 56 | |
RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 19.5 | 70 | |
RA2159 | PI103 | 0.1 | uM | 1 | IL18 | 18.0 | 60 | ||||
N2586 | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 136.0 | 66 | ||||
N2586 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 159.0 | 66 | |
N2586 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 214.0 | 59 | |
N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 186.0 | 56 | |
N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 175.0 | 81 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL18 | 90.0 | 56 | |
N2586 | PI103 | 0.1 | uM | 1 | IL18 | 39.0 | 63 | ||||
RA2159 | IL-6 | 100 | ug/mL | 1 | IL18 | 18.0 | 64 |