Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 48.0 43
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 39.0 73
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 45.0 76
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 36.0 54
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 27.0 58
RA2159 EO1428 1.0
uM
 3
IL-1RA
 19.0 70
N2586 TNF-a 100
ng/mL
 3
IL-1RA
 42.0 73
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 39.0 53
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 44.0 67
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 22.0 53
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 31.5 52
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 45.0 55
N2586 EO1428 1.0
uM
 3
IL-1RA
 21.0 61
0
IL-1RA
 17.0 53
RA2159 3
IL-1RA
 16.0 63
RA2159 PD184352 0.1
uM
 3
IL-1RA
 23.5 54
RA2159 Lestaurtinib 0.3
uM
 3
IL-1RA
 18.5 42
RA2159 Ruxolitinib 0.3
uM
 3
IL-1RA
 20.0 60
RA2159 Tofacitinib 0.3
uM
 3
IL-1RA
 17.0 43
RA2159 IKK16 2.0
uM
 3
IL-1RA
 19.0 64
RA2159 3
IL-1RA
 21.0 63
N2586 3
IL-1RA
 29.5 62
N2586 PD184352 0.1
uM
 3
IL-1RA
 22.0 72
N2586 Lestaurtinib 0.3
uM
 3
IL-1RA
 21.0 47
N2586 Ruxolitinib 0.3
uM
 3
IL-1RA
 22.0 40