Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TNFb
 104.0 50
RA2159 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TNFb
 70.0 60
RA2159 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TNFb
 84.5 56
RA2159 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
TNFb
 88.0 49
N2586 Adiponectin 5
ng/mL
 3
TNFb
 77.5 50
N2586 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
TNFb
 71.0 61
N2586 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TNFb
 72.0 50
N2586 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TNFb
 72.0 47
N2586 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TNFb
 65.5 44
N2586 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
TNFb
 85.0 67
RA2159 IGF-I 100
ug/mL
 3
TNFb
 50.0 56
RA2159 PD184352 0.1
uM
 IGF-I 100
ug/mL
 3
TNFb
 58.0 56
RA2159 Lestaurtinib 0.3
uM
 IGF-I 100
ug/mL
 3
TNFb
 66.0 63
RA2159 Ruxolitinib 0.3
uM
 IGF-I 100
ug/mL
 3
TNFb
 43.0 57
RA2159 Tofacitinib 0.3
uM
 IGF-I 100
ug/mL
 3
TNFb
 39.0 52
RA2159 IKK16 2.0
uM
 IGF-I 100
ug/mL
 3
TNFb
 37.5 52
RA2159 3
TNFb
 38.0 56
N2586 IGF-I 100
ug/mL
 3
TNFb
 46.0 61
N2586 PD184352 0.1
uM
 IGF-I 100
ug/mL
 3
TNFb
 53.0 80
N2586 Lestaurtinib 0.3
uM
 IGF-I 100
ug/mL
 3
TNFb
 31.0 55
N2586 Ruxolitinib 0.3
uM
 IGF-I 100
ug/mL
 3
TNFb
 336.0 57
N2586 Tofacitinib 0.3
uM
 IGF-I 100
ug/mL
 3
TNFb
 39.0 63
N2586 IKK16 2.0
uM
 IGF-I 100
ug/mL
 3
TNFb
 39.0 53
N2586 3
TNFb
 56.0 58
RA2159 EGF 100
ng/mL
 3
TNFb
 44.0 50