Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 PI103 0.1
uM
 1
b-NGF
 49.0 48
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 308.0 57
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 279.0 59
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 125.0 38
N2586 PI103 0.1
uM
 1
b-NGF
 76.0 54
0
b-NGF
 10.0 50
RA2159 1
b-NGF
 41.0 59
RA2159 Lestaurtinib 0.3
uM
 1
b-NGF
 38.0 66
RA2159 Ruxolitinib 0.3
uM
 1
b-NGF
 49.0 57
RA2159 1
b-NGF
 49.0 82
N2586 1
b-NGF
 92.0 71
N2586 Lestaurtinib 0.3
uM
 1
b-NGF
 90.0 69
N2586 Ruxolitinib 0.3
uM
 1
b-NGF
 114.0 55
0
b-NGF
 8.5 58
0
b-NGF
 11.0 40
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
b-NGF
 188.0 69
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 126.0 75
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
b-NGF
 62.0 61
RA2159 EO1428 1.0
uM
 1
b-NGF
 46.0 44
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
b-NGF
 229.0 40
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 265.0 35
RA2159 IL-1 alpha 100
ng/mL
 1
b-NGF
 155.0 57
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 140.0 93
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
b-NGF
 43.0 63
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
b-NGF
 45.0 68