Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2586 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IL12(p40) | 62.0 | 62 | |
N2586 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 3 | IL12(p40) | 49.0 | 71 | |
RA2159 | Leptin | 1 | ng/mL | 3 | IL12(p40) | 52.0 | 51 | ||||
RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL12(p40) | 46.0 | 47 | |
RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL12(p40) | 50.0 | 57 | |
RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL12(p40) | 52.0 | 54 | |
RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL12(p40) | 51.5 | 78 | |
RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL12(p40) | 50.0 | 59 | |
N2586 | Leptin | 1 | ng/mL | 3 | IL12(p40) | 42.0 | 70 | ||||
N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL12(p40) | 56.5 | 60 | |
N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL12(p40) | 54.5 | 76 | |
N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL12(p40) | 47.0 | 61 | |
N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL12(p40) | 52.0 | 61 | |
N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL12(p40) | 54.0 | 67 | |
RA2159 | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 84.0 | 57 | ||||
RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 84.5 | 78 | |
RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 104.5 | 66 | |
RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 76.0 | 61 | |
RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 85.0 | 62 | |
RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 94.0 | 72 | |
N2586 | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 87.0 | 83 | ||||
N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 93.5 | 66 | |
N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 78.0 | 55 | |
N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 89.0 | 50 | |
N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL12(p40) | 82.0 | 41 |