Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-1RA | 32.5 | 50 | |
| RA2159 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 1 | IL-1RA | 32.0 | 63 | |
| RA2159 | Sigma A6730 | 3.0 | uM | 1 | IL-1RA | 18.0 | 53 | ||||
| N2586 | IL-6 | 100 | ug/mL | 1 | IL-1RA | 29.0 | 90 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 1 | IL-1RA | 24.5 | 54 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-1RA | 28.0 | 58 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-1RA | 37.0 | 41 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-1RA | 25.0 | 64 | |
| N2586 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 1 | IL-1RA | 32.5 | 68 | |
| N2586 | Sigma A6730 | 3.0 | uM | 1 | IL-1RA | 28.0 | 44 | ||||
| RA2159 | IL-17A | 100 | ng/mL | 1 | IL-1RA | 24.0 | 67 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 1 | IL-1RA | 26.0 | 57 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-1RA | 26.0 | 53 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-1RA | 25.0 | 50 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-1RA | 27.5 | 56 | |
| RA2159 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | IL-1RA | 24.0 | 78 | |
| N2586 | IL-17A | 100 | ng/mL | 1 | IL-1RA | 31.0 | 67 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 1 | IL-1RA | 27.0 | 57 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-1RA | 30.0 | 67 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-1RA | 22.0 | 69 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-1RA | 25.0 | 69 | |
| N2586 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | IL-1RA | 24.0 | 59 | |
| RA2159 | 1 | IL-1RA | 27.5 | 64 | |||||||
| RA2159 | PD184352 | 0.1 | uM | 1 | IL-1RA | 25.5 | 68 | ||||
| RA2159 | Lestaurtinib | 0.3 | uM | 1 | IL-1RA | 23.0 | 64 |