Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
Poly(I:C) 2
ug/mL
 0
IFN-g
 13.0 32
0
IL-1RA
 21.0 52
RA2159 1
IL-1RA
 28.0 66
RA2159 PD184352 0.1
uM
 1
IL-1RA
 24.0 53
RA2159 Lestaurtinib 0.3
uM
 1
IL-1RA
 26.0 69
RA2159 Ruxolitinib 0.3
uM
 1
IL-1RA
 27.0 60
RA2159 Tofacitinib 0.3
uM
 1
IL-1RA
 24.0 69
RA2159 IKK16 2.0
uM
 1
IL-1RA
 28.0 50
RA2159 1
IL-1RA
 26.0 55
N2586 1
IL-1RA
 24.0 65
N2586 PD184352 0.1
uM
 1
IL-1RA
 24.0 55
N2586 Lestaurtinib 0.3
uM
 1
IL-1RA
 24.0 49
N2586 Ruxolitinib 0.3
uM
 1
IL-1RA
 27.0 72
N2586 Tofacitinib 0.3
uM
 1
IL-1RA
 25.0 63
N2586 IKK16 2.0
uM
 1
IL-1RA
 23.5 56
N2586 1
IL-1RA
 24.0 31
0
IL-1RA
 20.0 72
0
IL-1RA
 22.0 35
RA2159 TNF-a 100
ng/mL
 1
IL-1RA
 43.5 46
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 43.0 66
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 46.5 54
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 36.0 65
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 49.0 47
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 36.0 72
RA2159 EO1428 1.0
uM
 1
IL-1RA
 27.0 60