Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-15 | 154.0 | 65 | |
| N2586 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-15 | 137.5 | 56 | |
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-15 | 121.0 | 41 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL-15 | 110.0 | 75 | |
| N2586 | EO1428 | 1.0 | uM | 1 | IL-15 | 123.5 | 42 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 119.0 | 67 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 120.0 | 59 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 90.5 | 62 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 106.5 | 74 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 119.0 | 59 | |
| RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 79.5 | 58 | |
| RA2159 | PI103 | 0.1 | uM | 1 | IL-15 | 78.5 | 84 | ||||
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 122.5 | 58 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 127.0 | 53 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 98.5 | 60 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 123.0 | 70 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 119.0 | 51 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-15 | 95.5 | 50 | |
| N2586 | PI103 | 0.1 | uM | 1 | IL-15 | 83.0 | 63 | ||||
| RA2159 | IL-6 | 100 | ug/mL | 1 | IL-15 | 95.5 | 50 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 1 | IL-15 | 88.5 | 58 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-15 | 86.0 | 70 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-15 | 121.0 | 67 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-15 | 103.0 | 59 | |
| RA2159 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 1 | IL-15 | 105.5 | 46 |