Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-8 | 6943.0 | 91 | |
| RA2159 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-8 | 12111.0 | 99 | |
| RA2159 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-8 | 10584.0 | 67 | |
| RA2159 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL-8 | 2612.0 | 77 | |
| RA2159 | EO1428 | 1.0 | uM | 1 | IL-8 | 384.0 | 82 | ||||
| N2586 | TNF-a | 100 | ng/mL | 1 | IL-8 | 11713.0 | 63 | ||||
| N2586 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 1 | IL-8 | 8177.5 | 70 | |
| N2586 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-8 | 14119.0 | 57 | |
| N2586 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-8 | 13379.0 | 73 | |
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-8 | 11503.0 | 59 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL-8 | 8822.0 | 73 | |
| N2586 | EO1428 | 1.0 | uM | 1 | IL-8 | 907.0 | 33 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 13785.0 | 74 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 8406.0 | 90 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 8135.0 | 53 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 12554.0 | 74 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 12033.0 | 78 | |
| RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 660.0 | 96 | |
| RA2159 | PI103 | 0.1 | uM | 1 | IL-8 | 887.0 | 68 | ||||
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 12084.0 | 63 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 11395.5 | 86 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 9238.0 | 73 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 10480.0 | 73 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 12188.5 | 70 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-8 | 4771.0 | 51 |