Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IL-1 alpha 100
ng/mL
 3
IL-6
 31911.0 61
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 25273.0 59
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 16489.0 71
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 31329.5 78
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 31957.0 69
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 7018.0 69
RA2159 PI103 0.1
uM
 3
IL-6
 7082.5 62
N2586 IL-1 alpha 100
ng/mL
 3
IL-6
 31911.0 79
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 21555.0 65
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 32595.5 74
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 31181.0 56
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 12525.0 59
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 29391.0 58
N2586 PI103 0.1
uM
 3
IL-6
 5807.5 80
0
IL-6
 15.0 57
RA2159 TNF-a 100
ng/mL
 3
IL-6
 20506.0 57
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
IL-6
 18134.0 42
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 11209.0 61
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 18339.5 92
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 17997.0 60
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 10959.5 60
RA2159 EO1428 1.0
uM
 3
IL-6
 7427.0 69
N2586 TNF-a 100
ng/mL
 3
IL-6
 24874.5 78
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
IL-6
 15591.0 52
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 26482.0 51