Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA2159 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IL-6 | 5500.5 | 82 | |
RA2159 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 3 | IL-6 | 5111.0 | 67 | |
N2586 | Visfatin | 1 | ng/mL | 3 | IL-6 | 6950.5 | 70 | ||||
N2586 | PD184352 | 0.1 | uM | Visfatin | 1 | ng/mL | 3 | IL-6 | 5715.0 | 63 | |
N2586 | Lestaurtinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IL-6 | 5501.0 | 80 | |
N2586 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IL-6 | 6296.5 | 56 | |
N2586 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IL-6 | 5599.0 | 54 | |
N2586 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 3 | IL-6 | 6009.0 | 71 | |
RA2159 | Leptin | 1 | ng/mL | 3 | IL-6 | 7253.0 | 70 | ||||
RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL-6 | 5142.0 | 65 | |
RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-6 | 5670.5 | 68 | |
RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-6 | 6947.0 | 71 | |
RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-6 | 5675.0 | 83 | |
RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL-6 | 5613.0 | 67 | |
N2586 | Leptin | 1 | ng/mL | 3 | IL-6 | 6926.0 | 85 | ||||
N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL-6 | 5821.0 | 72 | |
N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-6 | 5723.0 | 75 | |
N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-6 | 6234.0 | 67 | |
N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-6 | 6349.5 | 60 | |
N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL-6 | 5891.5 | 80 | |
RA2159 | Adiponectin | 5 | ng/mL | 3 | IL-6 | 6845.0 | 65 | ||||
RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL-6 | 5705.5 | 72 | |
RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-6 | 6431.5 | 74 | |
RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-6 | 6935.0 | 55 | |
RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-6 | 6692.5 | 86 |