Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Tofacitinib | 0.3 | uM | 1 | IP-10 | 9.5 | 66 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | IP-10 | 11.5 | 50 | ||||
| N2586 | 1 | IP-10 | 14.0 | 37 | |||||||
| 0 | IP-10 | 10.0 | 67 | ||||||||
| 0 | IP-10 | 12.0 | 59 | ||||||||
| RA2159 | TNF-a | 100 | ng/mL | 1 | IP-10 | 1727.0 | 69 | ||||
| RA2159 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 1692.0 | 76 | |
| RA2159 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 1471.5 | 70 | |
| RA2159 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 438.0 | 95 | |
| RA2159 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 804.0 | 63 | |
| RA2159 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 25.5 | 76 | |
| RA2159 | EO1428 | 1.0 | uM | 1 | IP-10 | 13.0 | 85 | ||||
| N2586 | TNF-a | 100 | ng/mL | 1 | IP-10 | 985.0 | 74 | ||||
| N2586 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 1386.0 | 65 | |
| N2586 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 260.0 | 73 | |
| N2586 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 604.0 | 84 | |
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 553.0 | 65 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 79.0 | 63 | |
| N2586 | EO1428 | 1.0 | uM | 1 | IP-10 | 14.5 | 48 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 182.5 | 86 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 156.0 | 87 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 44.0 | 71 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 203.0 | 71 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 160.0 | 68 | |
| RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 13.0 | 88 |