Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-6 | 3542.0 | 75 | |
| N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-6 | 4321.5 | 38 | |
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-6 | 4527.5 | 60 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL-6 | 4055.5 | 62 | |
| N2586 | 1 | IL-6 | 5486.0 | 71 | |||||||
| RA2159 | Adiponectin | 5 | ng/mL | 1 | IL-6 | 6922.0 | 71 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-6 | 2414.5 | 60 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-6 | 2255.0 | 71 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-6 | 6312.0 | 49 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-6 | 5302.5 | 84 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-6 | 4638.0 | 78 | |
| N2586 | Adiponectin | 5 | ng/mL | 1 | IL-6 | 4267.5 | 60 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-6 | 5898.5 | 46 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-6 | 3859.0 | 59 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-6 | 3755.0 | 43 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-6 | 2774.0 | 39 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-6 | 4844.5 | 46 | |
| RA2159 | Leptin | 1 | ng/mL | 1 | IL-6 | 5824.5 | 66 | ||||
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | IL-6 | 4688.0 | 53 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-6 | 4258.0 | 75 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-6 | 5135.0 | 61 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-6 | 5233.0 | 70 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 1 | IL-6 | 3856.0 | 46 | |
| N2586 | Leptin | 1 | ng/mL | 1 | IL-6 | 5693.5 | 40 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | IL-6 | 4258.0 | 59 |