Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 13639.5 | 64 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 31145.0 | 72 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 29507.0 | 76 | |
| RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 7497.0 | 66 | |
| RA2159 | PI103 | 0.1 | uM | 1 | IL-6 | 6146.0 | 79 | ||||
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 32328.0 | 63 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 28210.0 | 67 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 24911.0 | 79 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 31782.0 | 49 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 31713.5 | 68 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 14575.0 | 49 | |
| N2586 | PI103 | 0.1 | uM | 1 | IL-6 | 5266.0 | 68 | ||||
| RA2159 | IL-6 | 100 | ug/mL | 1 | IL-6 | 20611.5 | 66 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 1 | IL-6 | 16937.5 | 56 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-6 | 14230.5 | 50 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-6 | 16471.0 | 81 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-6 | 16433.0 | 79 | |
| RA2159 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 1 | IL-6 | 18473.0 | 70 | |
| RA2159 | Sigma A6730 | 3.0 | uM | 1 | IL-6 | 4752.5 | 58 | ||||
| N2586 | IL-6 | 100 | ug/mL | 1 | IL-6 | 16903.0 | 82 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 1 | IL-6 | 14037.5 | 72 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-6 | 16593.0 | 53 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-6 | 26527.0 | 57 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | IL-6 | 13380.0 | 73 | |
| N2586 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 1 | IL-6 | 17938.5 | 72 |