Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
0
IL-1B
 10.0 56
RA2159 TNF-a 100
ng/mL
 3
IL-1B
 81.0 67
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
IL-1B
 116.0 47
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 102.5 62
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 62.5 72
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 49.0 53
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1B
 47.0 71
RA2159 EO1428 1.0
uM
 3
IL-1B
 11.0 50
N2586 TNF-a 100
ng/mL
 3
IL-1B
 42.0 63
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
IL-1B
 38.0 53
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 55.0 77
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 25.0 65
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 31.0 62
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1B
 45.0 69
N2586 EO1428 1.0
uM
 3
IL-1B
 12.0 54
0
IL-1B
 11.0 53
RA2159 3
IL-1B
 15.0 63
RA2159 PD184352 0.1
uM
 3
IL-1B
 61.0 58
RA2159 Lestaurtinib 0.3
uM
 3
IL-1B
 17.5 54
RA2159 Ruxolitinib 0.3
uM
 3
IL-1B
 37.0 62
RA2159 Tofacitinib 0.3
uM
 3
IL-1B
 24.5 34
RA2159 IKK16 2.0
uM
 3
IL-1B
 12.0 60
RA2159 3
IL-1B
 12.5 48
N2586 3
IL-1B
 13.0 68
N2586 PD184352 0.1
uM
 3
IL-1B
 12.0 63