Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
Leptin 1
ng/mL
 0
IL-2
 46.0 59
Visfatin 1
ng/mL
 0
IL-2
 44.0 42
Poly(I:C) 2
ug/mL
 0
IL-2
 49.0 53
0
IL-1B
 14.0 59
RA2159 1
IL-1B
 60.0 55
RA2159 PD184352 0.1
uM
 1
IL-1B
 37.0 62
RA2159 Lestaurtinib 0.3
uM
 1
IL-1B
 26.5 58
RA2159 Ruxolitinib 0.3
uM
 1
IL-1B
 15.0 61
RA2159 Tofacitinib 0.3
uM
 1
IL-1B
 19.0 67
RA2159 IKK16 2.0
uM
 1
IL-1B
 20.0 52
RA2159 1
IL-1B
 16.0 50
N2586 1
IL-1B
 17.5 68
N2586 PD184352 0.1
uM
 1
IL-1B
 19.0 56
N2586 Lestaurtinib 0.3
uM
 1
IL-1B
 15.5 46
N2586 Ruxolitinib 0.3
uM
 1
IL-1B
 16.0 59
N2586 Tofacitinib 0.3
uM
 1
IL-1B
 19.0 55
N2586 IKK16 2.0
uM
 1
IL-1B
 20.0 37
N2586 1
IL-1B
 18.0 27
0
IL-1B
 13.0 53
0
IL-1B
 17.0 49
RA2159 TNF-a 100
ng/mL
 1
IL-1B
 53.0 56
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
IL-1B
 49.0 51
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 80.0 55
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 39.0 69
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1B
 49.0 63