Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
TNF-a 100
ng/mL
 0
IL-5
 13.0 64
IL-1 alpha 100
ng/mL
 0
IL-5
 11.0 58
IL-6 100
ug/mL
 0
IL-5
 10.0 51
IL-17A 100
ng/mL
 0
IL-5
 8.0 51
EGF 100
ng/mL
 0
IL-5
 10.0 57
IGF-I 100
ug/mL
 0
IL-5
 10.5 56
Adiponectin 5
ng/mL
 0
IL-5
 14.0 54
Leptin 1
ng/mL
 0
IL-5
 10.0 51
Visfatin 1
ng/mL
 0
IL-5
 8.0 49
Poly(I:C) 2
ug/mL
 0
IL-5
 9.0 55
0
GM-CSF
 274.5 56
RA2159 1
GM-CSF
 292.0 65
RA2159 PD184352 0.1
uM
 1
GM-CSF
 268.0 55
RA2159 Lestaurtinib 0.3
uM
 1
GM-CSF
 285.5 60
RA2159 Ruxolitinib 0.3
uM
 1
GM-CSF
 279.0 57
RA2159 Tofacitinib 0.3
uM
 1
GM-CSF
 273.5 62
RA2159 IKK16 2.0
uM
 1
GM-CSF
 268.5 52
RA2159 1
GM-CSF
 284.0 63
N2586 1
GM-CSF
 257.5 60
N2586 PD184352 0.1
uM
 1
GM-CSF
 275.0 61
N2586 Lestaurtinib 0.3
uM
 1
GM-CSF
 277.0 33
N2586 Ruxolitinib 0.3
uM
 1
GM-CSF
 289.0 67
N2586 Tofacitinib 0.3
uM
 1
GM-CSF
 284.0 56
N2586 IKK16 2.0
uM
 1
GM-CSF
 241.5 54
N2586 1
GM-CSF
 311.0 39