Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
M-CSF
 136.0 55
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
M-CSF
 107.0 89
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
M-CSF
 86.0 52
N2586 IL-17A 100
ng/mL
 3
M-CSF
 190.0 73
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
M-CSF
 180.5 76
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
M-CSF
 137.5 60
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
M-CSF
 295.0 77
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
M-CSF
 130.5 64
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
M-CSF
 128.0 65
RA2159 IL-6 100
ug/mL
 3
M-CSF
 87.0 53
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
M-CSF
 97.0 70
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
M-CSF
 82.5 74
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
M-CSF
 101.5 58
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
M-CSF
 100.0 80
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
M-CSF
 79.0 71
RA2159 Sigma A6730 3.0
uM
 3
M-CSF
 115.0 59
N2586 IL-6 100
ug/mL
 3
M-CSF
 224.0 77
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
M-CSF
 153.0 55
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
M-CSF
 126.0 54
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
M-CSF
 150.0 61
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
M-CSF
 140.0 75
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
M-CSF
 126.0 63
N2586 Sigma A6730 3.0
uM
 3
M-CSF
 154.0 65
RA2159 IL-1 alpha 100
ng/mL
 3
M-CSF
 233.0 80
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 185.0 70