Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IKK16 2.0
uM
 Leptin 1
ng/mL
 3
TRAIL
 41.5 72
RA2159 Adiponectin 5
ng/mL
 3
TRAIL
 33.5 56
RA2159 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
TRAIL
 32.0 86
RA2159 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TRAIL
 34.0 62
RA2159 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TRAIL
 29.0 67
RA2159 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TRAIL
 34.0 56
RA2159 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
TRAIL
 33.0 76
N2586 Adiponectin 5
ng/mL
 3
TRAIL
 57.5 82
N2586 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
TRAIL
 56.0 54
N2586 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TRAIL
 48.5 54
N2586 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TRAIL
 53.0 67
N2586 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
TRAIL
 48.0 57
N2586 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
TRAIL
 46.0 74
RA2159 IGF-I 100
ug/mL
 3
TRAIL
 25.0 75
RA2159 PD184352 0.1
uM
 IGF-I 100
ug/mL
 3
TRAIL
 26.5 82
RA2159 Lestaurtinib 0.3
uM
 IGF-I 100
ug/mL
 3
TRAIL
 24.0 58
RA2159 Ruxolitinib 0.3
uM
 IGF-I 100
ug/mL
 3
TRAIL
 23.0 57
RA2159 Tofacitinib 0.3
uM
 IGF-I 100
ug/mL
 3
TRAIL
 24.0 63
RA2159 IKK16 2.0
uM
 IGF-I 100
ug/mL
 3
TRAIL
 25.0 64
RA2159 3
TRAIL
 28.0 65
N2586 IGF-I 100
ug/mL
 3
TRAIL
 55.0 68
N2586 PD184352 0.1
uM
 IGF-I 100
ug/mL
 3
TRAIL
 56.5 72
N2586 Lestaurtinib 0.3
uM
 IGF-I 100
ug/mL
 3
TRAIL
 40.0 59
N2586 Ruxolitinib 0.3
uM
 IGF-I 100
ug/mL
 3
TRAIL
 60.0 79
N2586 Tofacitinib 0.3
uM
 IGF-I 100
ug/mL
 3
TRAIL
 36.0 75