Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 PI103 0.1
uM
1
SCF
49.0 39
RA2159 IL-6 100
ug/mL
1
SCF
41.0 67
RA2159 PD184352 0.1
uM
IL-6 100
ug/mL
1
SCF
47.0 72
RA2159 Lestaurtinib 0.3
uM
IL-6 100
ug/mL
1
SCF
37.0 50
RA2159 Ruxolitinib 0.3
uM
IL-6 100
ug/mL
1
SCF
35.0 62
RA2159 Tofacitinib 0.3
uM
IL-6 100
ug/mL
1
SCF
43.0 71
RA2159 IKK16 2.0
uM
IL-6 100
ug/mL
1
SCF
37.0 64
RA2159 Sigma A6730 3.0
uM
1
SCF
45.0 75
N2586 IL-6 100
ug/mL
1
SCF
64.5 60
N2586 PD184352 0.1
uM
IL-6 100
ug/mL
1
SCF
58.0 61
N2586 Lestaurtinib 0.3
uM
IL-6 100
ug/mL
1
SCF
58.0 63
N2586 Ruxolitinib 0.3
uM
IL-6 100
ug/mL
1
SCF
65.0 49
N2586 Tofacitinib 0.3
uM
IL-6 100
ug/mL
1
SCF
51.0 57
N2586 IKK16 2.0
uM
IL-6 100
ug/mL
1
SCF
56.0 46
N2586 Sigma A6730 3.0
uM
1
SCF
76.0 67
RA2159 IL-17A 100
ng/mL
1
SCF
41.5 60
RA2159 PD184352 0.1
uM
IL-17A 100
ng/mL
1
SCF
33.0 65
RA2159 Lestaurtinib 0.3
uM
IL-17A 100
ng/mL
1
SCF
34.0 73
RA2159 Ruxolitinib 0.3
uM
IL-17A 100
ng/mL
1
SCF
39.0 80
RA2159 Tofacitinib 0.3
uM
IL-17A 100
ng/mL
1
SCF
45.0 69
RA2159 IKK16 2.0
uM
IL-17A 100
ng/mL
1
SCF
47.0 61
N2586 IL-17A 100
ng/mL
1
SCF
84.0 47
N2586 PD184352 0.1
uM
IL-17A 100
ng/mL
1
SCF
70.0 49
N2586 Lestaurtinib 0.3
uM
IL-17A 100
ng/mL
1
SCF
75.0 46
N2586 Ruxolitinib 0.3
uM
IL-17A 100
ng/mL
1
SCF
64.0 41