Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
IL3
50.5 70
RA2159 PI103 0.1
uM
1
IL3
54.0 70
N2586 IL-1 alpha 100
ng/mL
1
IL3
51.0 61
N2586 PD184352 0.1
uM
IL-1 alpha 100
ng/mL
1
IL3
54.5 64
N2586 Lestaurtinib 0.3
uM
IL-1 alpha 100
ng/mL
1
IL3
58.0 63
N2586 Ruxolitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
IL3
53.0 75
N2586 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
1
IL3
61.0 44
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
IL3
57.0 40
N2586 PI103 0.1
uM
1
IL3
40.0 55
RA2159 IL-6 100
ug/mL
1
IL3
48.0 50
RA2159 PD184352 0.1
uM
IL-6 100
ug/mL
1
IL3
46.0 67
RA2159 Lestaurtinib 0.3
uM
IL-6 100
ug/mL
1
IL3
44.0 49
RA2159 Ruxolitinib 0.3
uM
IL-6 100
ug/mL
1
IL3
44.0 72
RA2159 Tofacitinib 0.3
uM
IL-6 100
ug/mL
1
IL3
45.0 85
RA2159 IKK16 2.0
uM
IL-6 100
ug/mL
1
IL3
45.0 64
RA2159 Sigma A6730 3.0
uM
1
IL3
46.0 84
N2586 IL-6 100
ug/mL
1
IL3
49.5 74
N2586 PD184352 0.1
uM
IL-6 100
ug/mL
1
IL3
40.0 45
N2586 Lestaurtinib 0.3
uM
IL-6 100
ug/mL
1
IL3
46.0 55
N2586 Ruxolitinib 0.3
uM
IL-6 100
ug/mL
1
IL3
44.5 52
N2586 Tofacitinib 0.3
uM
IL-6 100
ug/mL
1
IL3
50.0 57
N2586 IKK16 2.0
uM
IL-6 100
ug/mL
1
IL3
38.5 56
N2586 Sigma A6730 3.0
uM
1
IL3
68.5 56
RA2159 IL-17A 100
ng/mL
1
IL3
41.0 84
RA2159 PD184352 0.1
uM
IL-17A 100
ng/mL
1
IL3
41.0 72