Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | b-NGF | 65.0 | 70 | |
RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | b-NGF | 63.0 | 82 | |
RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | b-NGF | 76.0 | 59 | |
RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | b-NGF | 72.0 | 63 | |
RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | b-NGF | 69.5 | 64 | |
N2586 | Adiponectin | 5 | ng/mL | 3 | b-NGF | 138.0 | 69 | ||||
N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | b-NGF | 132.0 | 69 | |
N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | b-NGF | 103.0 | 62 | |
N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | b-NGF | 121.0 | 48 | |
N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | b-NGF | 114.0 | 41 | |
N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | b-NGF | 113.0 | 66 | |
RA2159 | IGF-I | 100 | ug/mL | 3 | b-NGF | 25.0 | 59 | ||||
RA2159 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 3 | b-NGF | 28.0 | 61 | |
RA2159 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | b-NGF | 27.0 | 64 | |
RA2159 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | b-NGF | 28.0 | 49 | |
RA2159 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | b-NGF | 33.0 | 66 | |
RA2159 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 3 | b-NGF | 32.0 | 47 | |
RA2159 | 3 | b-NGF | 33.0 | 65 | |||||||
N2586 | IGF-I | 100 | ug/mL | 3 | b-NGF | 97.5 | 52 | ||||
N2586 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 3 | b-NGF | 84.0 | 61 | |
N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | b-NGF | 59.0 | 57 | |
N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | b-NGF | 80.0 | 75 | |
N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | b-NGF | 44.5 | 58 | |
N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 3 | b-NGF | 58.5 | 52 | |
N2586 | 3 | b-NGF | 71.5 | 54 |