Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 1
IL18
 19.0 70
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
IL18
 14.0 55
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
IL18
 16.0 73
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
IL18
 18.0 80
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 1
IL18
 17.0 80
RA2159 Sigma A6730 3.0
uM
 1
IL18
 21.0 73
N2586 IL-6 100
ug/mL
 1
IL18
 64.0 53
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 1
IL18
 47.0 75
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
IL18
 45.0 95
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
IL18
 47.0 47
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
IL18
 41.0 63
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 1
IL18
 45.5 58
N2586 Sigma A6730 3.0
uM
 1
IL18
 63.5 72
RA2159 IL-17A 100
ng/mL
 1
IL18
 17.0 75
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 1
IL18
 17.0 76
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL18
 17.0 65
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL18
 19.0 84
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL18
 22.0 79
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
IL18
 20.0 65
N2586 IL-17A 100
ng/mL
 1
IL18
 74.0 43
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 1
IL18
 66.5 46
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL18
 74.5 44
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL18
 54.5 54
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
IL18
 55.5 52
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
IL18
 54.0 69