Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Protein Concentration Protein Conc Unit Antibody Name Antibody Concentration Antibody Conc Unit 2nd Antibody Name 2nd Antibody Concentration 2nd Antibody Conc Unit Replicate Mean log10(k) (a.u.) Mean tau (min) Surviving Fraction Classification Accuracy (theta_T) Classification Accuracy (fate boundary)
HeLa ICRP Bortezomib 100
nM
TNF10 1.0
ng/ml
1 -6.43 491.0887 1.000 0.99194 0.96774
HeLa ICRP Bortezomib 100
nM
TNF10 1.0
ng/ml
2 -6.32 468.5230 0.965 0.99344 0.91028
HeLa ICRP Bortezomib 100
nM
TNF10 5.0
ng/ml
1 -5.56 416.4737 0.358 0.94737 0.58947
HeLa ICRP Bortezomib 100
nM
TNF10 5.0
ng/ml
2 -5.53 404.8037 0.065 0.83770 0.38743
HeLa ICRP Bortezomib 100
nM
TNF10 5.0
ng/ml
3 -5.79 469.2892 0.407 0.88235 0.52941
HeLa ICRP Bortezomib 100
nM
TNF10 7.5
ng/ml
1 -5.38 333.0821 0.012 0.94807 0.44891
HeLa ICRP Bortezomib 100
nM
TNF10 7.5
ng/ml
2 -5.69 426.8136 0.208 0.91182 0.36673
HeLa ICRP Bortezomib 100
nM
TNF10 50.0
ng/ml
1 -4.84 188.4868 0.000 1.00000 0.89474
HeLa ICRP Bortezomib 100
nM
TNF10 50.0
ng/ml
2 -4.76 163.3246 0.000 0.99474 0.97544
HeLa ICRP Bortezomib 100
nM
TNF10 250.0
ng/ml
1 -4.31 66.9521 0.000 0.96986 0.90411
HeLa ICRP Bortezomib 100
nM
TNF10 250.0
ng/ml
2 -4.37 81.7724 0.002 0.99067 0.94403
HeLa ICRP Bortezomib 100
nM
TNF10 500.0
ng/ml
1 -4.25 57.6070 0.002 0.97623 0.83360
HeLa ICRP Bortezomib 100
nM
TNF10 500.0
ng/ml
2 -4.31 71.7160 0.000 0.97284 0.94815
HeLa ICRP Navitoclax 10
uM
TNF10 1.0
ng/ml
1 -6.45 316.4894 0.957 0.97872 0.82979
HeLa ICRP Navitoclax 10
uM
TNF10 1.0
ng/ml
2 -6.56 276.5333 0.964 0.98667 0.87556
HeLa ICRP Navitoclax 10
uM
TNF10 25.0
ng/ml
1 -5.21 240.5391 0.249 0.91826 0.63304
HeLa ICRP Navitoclax 10
uM
TNF10 25.0
ng/ml
2 -5.53 262.3197 0.542 0.88304 0.67641
HeLa ICRP Navitoclax 10
uM
TNF10 25.0
ng/ml
3 -5.47 247.7883 0.507 0.92034 0.67505
HeLa ICRP Navitoclax 10
uM
TNF10 50.0
ng/ml
1 -4.78 147.7273 0.121 0.93939 0.78788
HeLa ICRP Navitoclax 10
uM
TNF10 50.0
ng/ml
2 -4.89 170.8451 0.162 0.91080 0.78169
HeLa ICRP Navitoclax 10
uM
TNF10 250.0
ng/ml
1 -4.39 70.4229 0.016 0.98363 0.90177
HeLa ICRP Navitoclax 10
uM
TNF10 250.0
ng/ml
2 -4.29 57.5746 0.045 0.94030 0.85634
HeLa ICRP Navitoclax 10
uM
TNF10 250.0
ng/ml
3 -4.17 41.8056 0.039 0.93333 0.74722
HeLa ICRP Navitoclax 10
uM
TNF10 500.0
ng/ml
1 -4.30 54.0650 0.013 0.98211 0.80813
HeLa ICRP Navitoclax 10
uM
TNF10 500.0
ng/ml
2 -4.23 47.4504 0.018 0.94643 0.78770