Average variable importance in the projection (VIP) scores from the PLSR models analyzing the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20231)
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| Cell Line | Time Point | Time Point Unit | Variable | Average VIP Score |
|---|---|---|---|---|
| K2 | 5 | hr | cPARP | -0.49113 |
| K2 | 5 | hr | p-Histone H3(S10) | -0.35441 |
| K2 | 5 | hr | p27 Kip1 | -0.29404 |
| K2 | 10 | hr | p-p90RSK(S380) | 1.11520 |
| K2 | 10 | hr | p-p90RSK(T573) | 0.78331 |
| K2 | 10 | hr | p-AKT(T308) | 1.25190 |
| K2 | 10 | hr | p-AKT(S473) | -0.67104 |
| K2 | 10 | hr | p-mTOR(S2448) | 1.11510 |
| K2 | 10 | hr | p-p70S6K(T421/S424) | 1.33950 |
| K2 | 10 | hr | p-p70S6K(T389) | 1.24870 |
| K2 | 10 | hr | p-S6(S235/236) | 1.49360 |
| K2 | 10 | hr | p-AMPK(T172) | 0.75776 |
| K2 | 10 | hr | p-JNK(T183/Y185) | 1.07530 |
| K2 | 10 | hr | Total c-Jun | 1.34540 |
| K2 | 10 | hr | p-cJun(S63) | 1.12840 |
| K2 | 10 | hr | p-P38(T180/Y182) | 0.60218 |
| K2 | 10 | hr | p-HSP27(S82) | 0.49450 |
| K2 | 10 | hr | p-NFKB(S536) | 0.49598 |
| K2 | 10 | hr | Bim | -0.18648 |
| K2 | 10 | hr | cPARP | 0.75419 |
| K2 | 10 | hr | p-Histone H3(S10) | -0.23635 |
| K2 | 10 | hr | p27 Kip1 | -0.48401 |
| K2 | 24 | hr | p-p90RSK(S380) | NaN |
| K2 | 24 | hr | p-p90RSK(T573) | NaN |
| K2 | 24 | hr | p-AKT(T308) | 0.99821 |