Ibrutinib KINOMEscan - Dataset (ID:20222)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
200036 | AKT3 | 200036 | Q9Y243 | V-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); AKT3; Akt3/PKBg; DKFZp434N0250; PKBg; PKB-GAMMA; PRKBG; RAC-gamma; RAC-PK-gamma; STK-2 | KINOMEscan | Wild Type; Partial length | |||
200037 | ALK | 200037 | Q9UM73 | Anaplastic lymphoma receptor tyrosine kinase; ALK; CD246; NBLST3; TFG/ALK | KINOMEscan | Wild Type; Partial length | |||
200038 | AMPK-alpha1 | 200038 | Q13131 | Protein kinase, AMP-activated, alpha 2 catalytic subunit; AMPK; AMPKa1; AMPK-alpha1; MGC33776; MGC57364; PRKAA1 | KINOMEscan | Wild Type; Partial length | |||
200039 | AMPK-alpha2 | 200039 | P54646 | Protein kinase, AMP-activated, alpha 2 catalytic subunit; AMPK; AMPK2; AMPKa2; AMPK-alpha2; PRKAA; PRKAA2 | KINOMEscan | Wild Type; Partial length | |||
200040 | ANKK1 | 200040 | Q8NFD2 | Ankyrin repeat and kinase domain containing 1; ANKK1; PKK2; SgK288 | KINOMEscan | Wild Type; Partial length | |||
200033 | ADCK4 | 200033 | Q96D53 | AarF domain containing kinase 4; ADCK4; FLJ12229 | KINOMEscan | Wild Type; Full length | |||
200020 | ABL1(T315I)-nonphosphorylated | 200020 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | T315I | nonphosphorylated | Mutation (T315I); Partial length | |
200010 | ABL1(F317L)-phosphorylated | 200010 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317L | phosphorylated | Mutation (F317L); Partial length | |
200006 | ABL1(F317I)-nonphosphorylated | 200006 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | F317I | nonphosphorylated | Mutation (F317I); Partial length | |
200032 | ADCK3 | 200032 | Q8NI60 | Chaperone, ABC1 activity of bc1 complex homolog (S. pombe); ADCK3; ARCA2; CABC1; COQ8; MGC4849; SCAR9 | KINOMEscan | Wild Type; Full length | |||
200031 | ACVRL1 | 200031 | P37023 | Activin A receptor type II-like 1; ACVRL1; ACVRLK1; ALK1; ALK-1; HHT; HHT2; ORW2; SKR3; TSR-I | KINOMEscan | Wild Type; Partial length | |||
200018 | ABL1(Q252H)-phosphorylated | 200018 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Q252H | phosphorylated | Mutation (Q252H); Partial length | |
200051 | BMPR1B | 200051 | O00238 | Bone morphogenetic protein receptor, type IB; ALK6; ALK-6; BMPR1B; CDw293 | KINOMEscan | Wild Type; Partial length | |||
200030 | ACVR2B | 200030 | Q13705 | Activin A receptor, type IIB; ActR2B; ACTRIIB; ActR-IIB; ACVR2B; MGC116908 | KINOMEscan | Wild Type; Partial length | |||
200050 | BMPR1A | 200050 | P36894 | Bone morphogenetic protein receptor, type IA; 10q23del; ACVRLK3; ALK3; BMPR1A; CD292; SKR5 | KINOMEscan | Wild Type; Partial length | |||
200049 | BLK | 200049 | P51451 | Tyrosine-protein kinase BLK; B lymphoid tyrosine kinase; BLK; MGC10442 | KINOMEscan | Wild Type; Partial length | |||
200052 | BMPR2 | 200052 | Q13873 | Bone morphogenetic protein receptor, type II (serine/threonine kinase); BMPR2; BMPR3; BMPR-II; BMR2; BRK-3; FLJ41585; FLJ76945; PPH1; T-ALK | KINOMEscan | Wild Type; Partial length | |||
200053 | BMX | 200053 | P51813 | BMX non-receptor tyrosine kinase; BMX; ETK; Etk/BMX; PSCTK2; PSCTK3 | KINOMEscan | Wild Type; Full length | |||
200054 | BRAF | 200054 | P15056 | Serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B1; BRAF1; RAFB1 | KINOMEscan | Wild Type; Partial length | |||
200055 | BRAF(V600E) | 200055 | P15056 | V-raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1; B-RAF1; FLJ95109; MGC126806; MGC138284; RAFB1 | KINOMEscan | V600E | Mutation (V600E); Partial length | ||
200056 | PTK6 | 200056 | Q13882 | Protein tyrosine kinase 6; BRK; FLJ42088; PTK6 | KINOMEscan | Wild Type; Partial length | |||
200057 | BRSK1 | 200057 | Q8TDC3 | BR serine/threonine kinase 1; BRSK1; FLJ43009; KIAA1811 | KINOMEscan | Wild Type; Partial length | |||
200058 | BRSK2 | 200058 | Q8IWQ3 | BR serine/threonine kinase 2; BRSK2; C11orf7; FLJ41362; PEN11B; SAD1; STK29 | KINOMEscan | Wild Type; Full length | |||
200029 | ACVR2A | 200029 | P27037 | Activin A receptor, type IIA; ActR2; ACTRII; ACVR2; ACVR2A | KINOMEscan | Wild Type; Partial length | |||
200017 | ABL1(Q252H)-nonphosphorylated | 200017 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | Q252H | nonphosphorylated | Mutation (Q252H); Partial length |