Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selumetinib | COLO 858 | 0.0100 | uM | 48 | hr | 4824 | 203 | 1.0558 | 1.0530 | 0.0421 | 0.0490 | 4 |
| Selumetinib | COLO 858 | 0.0100 | uM | 72 | hr | 2967 | 226 | 0.9956 | 1.0453 | 0.0762 | 0.0753 | 1 |
| Selumetinib | COLO 858 | 0.0100 | uM | 72 | hr | 3111 | 263 | 1.0345 | 1.0453 | 0.0845 | 0.0753 | 2 |
| Selumetinib | COLO 858 | 0.0100 | uM | 72 | hr | 2804 | 190 | 0.9495 | 1.0453 | 0.0678 | 0.0753 | 3 |
| Selumetinib | COLO 858 | 0.0100 | uM | 72 | hr | 3567 | 259 | 1.2016 | 1.0453 | 0.0726 | 0.0753 | 4 |
| Selumetinib | COLO 858 | 0.0316 | uM | 24 | hr | 4920 | 215 | 1.5716 | 1.2379 | 0.0437 | 0.0433 | 1 |
| Selumetinib | COLO 858 | 0.0316 | uM | 24 | hr | 4825 | 206 | 1.5429 | 1.2379 | 0.0427 | 0.0433 | 2 |
| Selumetinib | COLO 858 | 0.0316 | uM | 24 | hr | 2812 | 131 | 0.8956 | 1.2379 | 0.0466 | 0.0433 | 3 |
| Selumetinib | COLO 858 | 0.0316 | uM | 24 | hr | 2937 | 118 | 0.9417 | 1.2379 | 0.0402 | 0.0433 | 4 |
| Selumetinib | COLO 858 | 0.0316 | uM | 48 | hr | 4684 | 203 | 1.0238 | 1.0642 | 0.0433 | 0.0473 | 1 |
| Selumetinib | COLO 858 | 0.0316 | uM | 48 | hr | 4836 | 235 | 1.0513 | 1.0642 | 0.0486 | 0.0473 | 2 |
| Selumetinib | COLO 858 | 0.0316 | uM | 48 | hr | 4893 | 268 | 1.0567 | 1.0642 | 0.0548 | 0.0473 | 3 |
| Selumetinib | COLO 858 | 0.0316 | uM | 48 | hr | 5141 | 218 | 1.1248 | 1.0642 | 0.0424 | 0.0473 | 4 |
| Selumetinib | COLO 858 | 0.0316 | uM | 72 | hr | 2089 | 141 | 0.7076 | 0.8432 | 0.0675 | 0.0678 | 1 |
| Selumetinib | COLO 858 | 0.0316 | uM | 72 | hr | 2609 | 166 | 0.8874 | 0.8432 | 0.0636 | 0.0678 | 2 |
| Selumetinib | COLO 858 | 0.0316 | uM | 72 | hr | 2153 | 160 | 0.7239 | 0.8432 | 0.0743 | 0.0678 | 3 |
| Selumetinib | COLO 858 | 0.0316 | uM | 72 | hr | 3106 | 204 | 1.0541 | 0.8432 | 0.0657 | 0.0678 | 4 |
| Selumetinib | COLO 858 | 0.1000 | uM | 24 | hr | 4139 | 216 | 1.3104 | 1.1195 | 0.0522 | 0.0474 | 1 |
| Selumetinib | COLO 858 | 0.1000 | uM | 24 | hr | 4510 | 209 | 1.4367 | 1.1195 | 0.0463 | 0.0474 | 2 |
| Selumetinib | COLO 858 | 0.1000 | uM | 24 | hr | 2663 | 115 | 0.8511 | 1.1195 | 0.0432 | 0.0474 | 3 |
| Selumetinib | COLO 858 | 0.1000 | uM | 24 | hr | 2767 | 133 | 0.8799 | 1.1195 | 0.0481 | 0.0474 | 4 |
| Selumetinib | COLO 858 | 0.1000 | uM | 48 | hr | 3129 | 244 | 0.6592 | 0.7022 | 0.0780 | 0.0649 | 1 |
| Selumetinib | COLO 858 | 0.1000 | uM | 48 | hr | 2998 | 160 | 0.6484 | 0.7022 | 0.0534 | 0.0649 | 2 |
| Selumetinib | COLO 858 | 0.1000 | uM | 48 | hr | 3495 | 231 | 0.7458 | 0.7022 | 0.0661 | 0.0649 | 3 |
| Selumetinib | COLO 858 | 0.1000 | uM | 48 | hr | 3525 | 219 | 0.7554 | 0.7022 | 0.0621 | 0.0649 | 4 |