Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Vemurafenib WM-115 3.1600
uM
 48
hr
 654 60 1.1992 0.8843 0.0917 0.1161 2
Vemurafenib WM-115 3.1600
uM
 48
hr
 369 55 0.6339 0.8843 0.1491 0.1161 3
Vemurafenib WM-115 3.1600
uM
 48
hr
 322 46 0.5572 0.8843 0.1429 0.1161 4
Vemurafenib WM-115 3.1600
uM
 72
hr
 1292 564 0.2401 0.2696 0.4365 0.4066 1
Vemurafenib WM-115 3.1600
uM
 72
hr
 1216 561 0.2161 0.2696 0.4614 0.4066 2
Vemurafenib WM-115 3.1600
uM
 72
hr
 1508 553 0.3150 0.2696 0.3667 0.4066 3
Vemurafenib WM-115 3.1600
uM
 72
hr
 1459 528 0.3071 0.2696 0.3619 0.4066 4
WM-115 0.0000
uM
 24
hr
 415 24 0.7468 0.0578 1
WM-115 0.0000
uM
 24
hr
 462 12 0.8594 0.0260 1
WM-115 0.0000
uM
 24
hr
 509 32 0.9110 0.0629 1
WM-115 0.0000
uM
 24
hr
 524 24 0.9549 0.0458 1
WM-115 0.0000
uM
 24
hr
 550 28 0.9969 0.0509 1
WM-115 0.0000
uM
 24
hr
 559 22 1.0256 0.0394 1
WM-115 0.0000
uM
 24
hr
 692 25 1.2739 0.0361 1
WM-115 0.0000
uM
 24
hr
 387 29 0.6837 0.0749 2
WM-115 0.0000
uM
 24
hr
 396 11 0.7353 0.0278 2
WM-115 0.0000
uM
 24
hr
 433 15 0.7983 0.0346 2
WM-115 0.0000
uM
 24
hr
 447 11 0.8327 0.0246 2
WM-115 0.0000
uM
 24
hr
 450 36 0.7907 0.0800 2
WM-115 0.0000
uM
 24
hr
 480 32 0.8556 0.0667 2
WM-115 0.0000
uM
 24
hr
 488 19 0.8957 0.0389 2
WM-115 0.0000
uM
 24
hr
 550 31 0.9912 0.0564 3
WM-115 0.0000
uM
 24
hr
 605 32 1.0943 0.0529 3
WM-115 0.0000
uM
 24
hr
 705 32 1.2853 0.0454 3
WM-115 0.0000
uM
 24
hr
 715 31 1.3063 0.0434 3