Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | WM-115 | 0.0316 | uM | 24 | hr | 952 | 55 | 1.7131 | 1.2214 | 0.0578 | 0.0561 | 4 |
| Vemurafenib | WM-115 | 0.0316 | uM | 48 | hr | 688 | 27 | 1.3345 | 1.2406 | 0.0392 | 0.0424 | 1 |
| Vemurafenib | WM-115 | 0.0316 | uM | 48 | hr | 847 | 30 | 1.6494 | 1.2406 | 0.0354 | 0.0424 | 2 |
| Vemurafenib | WM-115 | 0.0316 | uM | 48 | hr | 509 | 19 | 0.9893 | 1.2406 | 0.0373 | 0.0424 | 3 |
| Vemurafenib | WM-115 | 0.0316 | uM | 48 | hr | 520 | 30 | 0.9893 | 1.2406 | 0.0577 | 0.0424 | 4 |
| Vemurafenib | WM-115 | 0.0316 | uM | 72 | hr | 3269 | 100 | 1.0453 | 1.0495 | 0.0306 | 0.0317 | 1 |
| Vemurafenib | WM-115 | 0.0316 | uM | 72 | hr | 3224 | 98 | 1.0312 | 1.0495 | 0.0304 | 0.0317 | 2 |
| Vemurafenib | WM-115 | 0.0316 | uM | 72 | hr | 3384 | 97 | 1.0843 | 1.0495 | 0.0287 | 0.0317 | 3 |
| Vemurafenib | WM-115 | 0.0316 | uM | 72 | hr | 3265 | 121 | 1.0371 | 1.0495 | 0.0371 | 0.0317 | 4 |
| Vemurafenib | WM-115 | 0.1000 | uM | 24 | hr | 475 | 16 | 0.8766 | 1.1793 | 0.0337 | 0.0385 | 1 |
| Vemurafenib | WM-115 | 0.1000 | uM | 24 | hr | 505 | 19 | 0.9282 | 1.1793 | 0.0376 | 0.0385 | 2 |
| Vemurafenib | WM-115 | 0.1000 | uM | 24 | hr | 696 | 28 | 1.2758 | 1.1793 | 0.0402 | 0.0385 | 3 |
| Vemurafenib | WM-115 | 0.1000 | uM | 24 | hr | 895 | 38 | 1.6367 | 1.1793 | 0.0425 | 0.0385 | 4 |
| Vemurafenib | WM-115 | 0.1000 | uM | 48 | hr | 759 | 40 | 1.4516 | 1.4521 | 0.0527 | 0.0407 | 1 |
| Vemurafenib | WM-115 | 0.1000 | uM | 48 | hr | 942 | 36 | 1.8291 | 1.4521 | 0.0382 | 0.0407 | 2 |
| Vemurafenib | WM-115 | 0.1000 | uM | 48 | hr | 552 | 19 | 1.0761 | 1.4521 | 0.0344 | 0.0407 | 3 |
| Vemurafenib | WM-115 | 0.1000 | uM | 48 | hr | 747 | 28 | 1.4516 | 1.4521 | 0.0375 | 0.0407 | 4 |
| Vemurafenib | WM-115 | 0.1000 | uM | 72 | hr | 3317 | 85 | 1.0661 | 1.0710 | 0.0256 | 0.0278 | 1 |
| Vemurafenib | WM-115 | 0.1000 | uM | 72 | hr | 3280 | 96 | 1.0503 | 1.0710 | 0.0293 | 0.0278 | 2 |
| Vemurafenib | WM-115 | 0.1000 | uM | 72 | hr | 3452 | 83 | 1.1113 | 1.0710 | 0.0240 | 0.0278 | 3 |
| Vemurafenib | WM-115 | 0.1000 | uM | 72 | hr | 3309 | 107 | 1.0562 | 1.0710 | 0.0323 | 0.0278 | 4 |
| Vemurafenib | WM-115 | 0.3160 | uM | 24 | hr | 469 | 14 | 0.8690 | 1.1741 | 0.0299 | 0.0444 | 1 |
| Vemurafenib | WM-115 | 0.3160 | uM | 24 | hr | 439 | 15 | 0.8098 | 1.1741 | 0.0342 | 0.0444 | 2 |
| Vemurafenib | WM-115 | 0.3160 | uM | 24 | hr | 870 | 49 | 1.5680 | 1.1741 | 0.0563 | 0.0444 | 3 |
| Vemurafenib | WM-115 | 0.3160 | uM | 24 | hr | 805 | 46 | 1.4496 | 1.1741 | 0.0571 | 0.0444 | 4 |