Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | WM-115 | 0.1000 | uM | 72 | hr | 2002 | 254 | 0.5766 | 0.5938 | 0.1269 | 0.1586 | 2 |
| AZ-628 | WM-115 | 0.1000 | uM | 72 | hr | 2306 | 422 | 0.6215 | 0.5938 | 0.1830 | 0.1586 | 3 |
| AZ-628 | WM-115 | 0.1000 | uM | 72 | hr | 2245 | 450 | 0.5921 | 0.5938 | 0.2005 | 0.1586 | 4 |
| AZ-628 | WM-115 | 0.3160 | uM | 24 | hr | 634 | 46 | 1.1230 | 1.3651 | 0.0726 | 0.0725 | 1 |
| AZ-628 | WM-115 | 0.3160 | uM | 24 | hr | 446 | 47 | 0.7620 | 1.3651 | 0.1054 | 0.0725 | 2 |
| AZ-628 | WM-115 | 0.3160 | uM | 24 | hr | 1070 | 60 | 1.9290 | 1.3651 | 0.0561 | 0.0725 | 3 |
| AZ-628 | WM-115 | 0.3160 | uM | 24 | hr | 913 | 51 | 1.6463 | 1.3651 | 0.0559 | 0.0725 | 4 |
| AZ-628 | WM-115 | 0.3160 | uM | 48 | hr | 765 | 70 | 1.4031 | 1.1139 | 0.0915 | 0.1394 | 1 |
| AZ-628 | WM-115 | 0.3160 | uM | 48 | hr | 655 | 55 | 1.2113 | 1.1139 | 0.0840 | 0.1394 | 2 |
| AZ-628 | WM-115 | 0.3160 | uM | 48 | hr | 539 | 90 | 0.9065 | 1.1139 | 0.1670 | 0.1394 | 3 |
| AZ-628 | WM-115 | 0.3160 | uM | 48 | hr | 590 | 127 | 0.9347 | 1.1139 | 0.2153 | 0.1394 | 4 |
| AZ-628 | WM-115 | 0.3160 | uM | 72 | hr | 1638 | 780 | 0.2830 | 0.2813 | 0.4762 | 0.4195 | 1 |
| AZ-628 | WM-115 | 0.3160 | uM | 72 | hr | 1231 | 433 | 0.2632 | 0.2813 | 0.3518 | 0.4195 | 2 |
| AZ-628 | WM-115 | 0.3160 | uM | 72 | hr | 1473 | 611 | 0.2843 | 0.2813 | 0.4148 | 0.4195 | 3 |
| AZ-628 | WM-115 | 0.3160 | uM | 72 | hr | 1581 | 688 | 0.2946 | 0.2813 | 0.4352 | 0.4195 | 4 |
| AZ-628 | WM-115 | 1.0000 | uM | 24 | hr | 599 | 67 | 1.0160 | 0.8699 | 0.1119 | 0.1346 | 1 |
| AZ-628 | WM-115 | 1.0000 | uM | 24 | hr | 382 | 53 | 0.6283 | 0.8699 | 0.1387 | 0.1346 | 2 |
| AZ-628 | WM-115 | 1.0000 | uM | 24 | hr | 589 | 72 | 0.9874 | 0.8699 | 0.1222 | 0.1346 | 3 |
| AZ-628 | WM-115 | 1.0000 | uM | 24 | hr | 532 | 88 | 0.8480 | 0.8699 | 0.1654 | 0.1346 | 4 |
| AZ-628 | WM-115 | 1.0000 | uM | 48 | hr | 508 | 138 | 0.7470 | 0.6582 | 0.2717 | 0.3114 | 1 |
| AZ-628 | WM-115 | 1.0000 | uM | 48 | hr | 546 | 157 | 0.7854 | 0.6582 | 0.2876 | 0.3114 | 2 |
| AZ-628 | WM-115 | 1.0000 | uM | 48 | hr | 409 | 135 | 0.5532 | 0.6582 | 0.3301 | 0.3114 | 3 |
| AZ-628 | WM-115 | 1.0000 | uM | 48 | hr | 421 | 150 | 0.5471 | 0.6582 | 0.3563 | 0.3114 | 4 |
| AZ-628 | WM-115 | 1.0000 | uM | 72 | hr | 1310 | 893 | 0.1376 | 0.1723 | 0.6817 | 0.6442 | 1 |
| AZ-628 | WM-115 | 1.0000 | uM | 72 | hr | 1455 | 1092 | 0.1197 | 0.1723 | 0.7505 | 0.6442 | 2 |