Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
---|---|---|---|---|---|---|---|---|---|---|---|---|
SB590885 | COLO 858 | 0.1000 | uM | 72 | hr | 2023 | 148 | 0.6811 | 0.6054 | 0.0732 | 0.0770 | 3 |
SB590885 | COLO 858 | 0.1000 | uM | 72 | hr | 1799 | 156 | 0.5968 | 0.6054 | 0.0867 | 0.0770 | 4 |
SB590885 | COLO 858 | 0.3160 | uM | 24 | hr | 3906 | 310 | 1.2012 | 0.9462 | 0.0794 | 0.0792 | 1 |
SB590885 | COLO 858 | 0.3160 | uM | 24 | hr | 3628 | 265 | 1.1234 | 0.9462 | 0.0730 | 0.0792 | 2 |
SB590885 | COLO 858 | 0.3160 | uM | 24 | hr | 2427 | 198 | 0.7446 | 0.9462 | 0.0816 | 0.0792 | 3 |
SB590885 | COLO 858 | 0.3160 | uM | 24 | hr | 2335 | 193 | 0.7155 | 0.9462 | 0.0827 | 0.0792 | 4 |
SB590885 | COLO 858 | 0.3160 | uM | 48 | hr | 2420 | 386 | 0.4647 | 0.4309 | 0.1595 | 0.1530 | 1 |
SB590885 | COLO 858 | 0.3160 | uM | 48 | hr | 2302 | 303 | 0.4567 | 0.4309 | 0.1316 | 0.1530 | 2 |
SB590885 | COLO 858 | 0.3160 | uM | 48 | hr | 2126 | 354 | 0.4049 | 0.4309 | 0.1665 | 0.1530 | 3 |
SB590885 | COLO 858 | 0.3160 | uM | 48 | hr | 2056 | 317 | 0.3973 | 0.4309 | 0.1542 | 0.1530 | 4 |
SB590885 | COLO 858 | 0.3160 | uM | 72 | hr | 1604 | 205 | 0.5082 | 0.4942 | 0.1278 | 0.1411 | 1 |
SB590885 | COLO 858 | 0.3160 | uM | 72 | hr | 1446 | 208 | 0.4497 | 0.4942 | 0.1439 | 0.1411 | 2 |
SB590885 | COLO 858 | 0.3160 | uM | 72 | hr | 1689 | 231 | 0.5296 | 0.4942 | 0.1368 | 0.1411 | 3 |
SB590885 | COLO 858 | 0.3160 | uM | 72 | hr | 1596 | 249 | 0.4893 | 0.4942 | 0.1560 | 0.1411 | 4 |
SB590885 | COLO 858 | 1.0000 | uM | 24 | hr | 3802 | 442 | 1.1224 | 0.8828 | 0.1163 | 0.1227 | 1 |
SB590885 | COLO 858 | 1.0000 | uM | 24 | hr | 3560 | 418 | 1.0495 | 0.8828 | 0.1174 | 0.1227 | 2 |
SB590885 | COLO 858 | 1.0000 | uM | 24 | hr | 2420 | 302 | 0.7075 | 0.8828 | 0.1248 | 0.1227 | 3 |
SB590885 | COLO 858 | 1.0000 | uM | 24 | hr | 2248 | 297 | 0.6517 | 0.8828 | 0.1321 | 0.1227 | 4 |
SB590885 | COLO 858 | 1.0000 | uM | 48 | hr | 1847 | 368 | 0.3379 | 0.3407 | 0.1992 | 0.2373 | 1 |
SB590885 | COLO 858 | 1.0000 | uM | 48 | hr | 2089 | 494 | 0.3644 | 0.3407 | 0.2365 | 0.2373 | 2 |
SB590885 | COLO 858 | 1.0000 | uM | 48 | hr | 1912 | 487 | 0.3256 | 0.3407 | 0.2547 | 0.2373 | 3 |
SB590885 | COLO 858 | 1.0000 | uM | 48 | hr | 1976 | 511 | 0.3347 | 0.3407 | 0.2586 | 0.2373 | 4 |
SB590885 | COLO 858 | 1.0000 | uM | 72 | hr | 1260 | 372 | 0.3226 | 0.3809 | 0.2952 | 0.2676 | 1 |
SB590885 | COLO 858 | 1.0000 | uM | 72 | hr | 1357 | 359 | 0.3625 | 0.3809 | 0.2646 | 0.2676 | 2 |
SB590885 | COLO 858 | 1.0000 | uM | 72 | hr | 1559 | 383 | 0.4272 | 0.3809 | 0.2457 | 0.2676 | 3 |