Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | MMAC-SF | 3.1600 | uM | 72 | hr | 1255 | 798 | 0.1330 | 0.1411 | 0.6359 | 0.6202 | 4 |
| Selumetinib | MMAC-SF | 0.0032 | uM | 24 | hr | 1 | ||||||
| Selumetinib | MMAC-SF | 0.0032 | uM | 24 | hr | 2 | ||||||
| Selumetinib | MMAC-SF | 0.0032 | uM | 24 | hr | 2958 | 156 | 1.0894 | 1.1080 | 0.0527 | 0.0508 | 3 |
| Selumetinib | MMAC-SF | 0.0032 | uM | 24 | hr | 3047 | 149 | 1.1267 | 1.1080 | 0.0489 | 0.0508 | 4 |
| Selumetinib | MMAC-SF | 0.0032 | uM | 48 | hr | 3468 | 164 | 0.8710 | 0.9068 | 0.0473 | 0.0481 | 1 |
| Selumetinib | MMAC-SF | 0.0032 | uM | 48 | hr | 3317 | 146 | 0.8360 | 0.9068 | 0.0440 | 0.0481 | 2 |
| Selumetinib | MMAC-SF | 0.0032 | uM | 48 | hr | 3790 | 172 | 0.9538 | 0.9068 | 0.0454 | 0.0481 | 3 |
| Selumetinib | MMAC-SF | 0.0032 | uM | 48 | hr | 3882 | 216 | 0.9665 | 0.9068 | 0.0556 | 0.0481 | 4 |
| Selumetinib | MMAC-SF | 0.0032 | uM | 72 | hr | 3017 | 112 | 0.8451 | 0.9243 | 0.0371 | 0.0392 | 1 |
| Selumetinib | MMAC-SF | 0.0032 | uM | 72 | hr | 3389 | 134 | 0.9469 | 0.9243 | 0.0395 | 0.0392 | 2 |
| Selumetinib | MMAC-SF | 0.0032 | uM | 72 | hr | 3483 | 128 | 0.9760 | 0.9243 | 0.0368 | 0.0392 | 3 |
| Selumetinib | MMAC-SF | 0.0032 | uM | 72 | hr | 3339 | 145 | 0.9292 | 0.9243 | 0.0434 | 0.0392 | 4 |
| Selumetinib | MMAC-SF | 0.0100 | uM | 24 | hr | 1 | ||||||
| Selumetinib | MMAC-SF | 0.0100 | uM | 24 | hr | 2 | ||||||
| Selumetinib | MMAC-SF | 0.0100 | uM | 24 | hr | 2841 | 122 | 1.0571 | 1.0250 | 0.0429 | 0.0478 | 3 |
| Selumetinib | MMAC-SF | 0.0100 | uM | 24 | hr | 2696 | 142 | 0.9930 | 1.0250 | 0.0527 | 0.0478 | 4 |
| Selumetinib | MMAC-SF | 0.0100 | uM | 48 | hr | 3881 | 147 | 0.9844 | 1.0072 | 0.0379 | 0.0390 | 1 |
| Selumetinib | MMAC-SF | 0.0100 | uM | 48 | hr | 3763 | 135 | 0.9564 | 1.0072 | 0.0359 | 0.0390 | 2 |
| Selumetinib | MMAC-SF | 0.0100 | uM | 48 | hr | 4058 | 182 | 1.0218 | 1.0072 | 0.0449 | 0.0390 | 3 |
| Selumetinib | MMAC-SF | 0.0100 | uM | 48 | hr | 4203 | 158 | 1.0664 | 1.0072 | 0.0376 | 0.0390 | 4 |
| Selumetinib | MMAC-SF | 0.0100 | uM | 72 | hr | 2495 | 104 | 0.6956 | 0.7588 | 0.0417 | 0.0379 | 1 |
| Selumetinib | MMAC-SF | 0.0100 | uM | 72 | hr | 2753 | 112 | 0.7683 | 0.7588 | 0.0407 | 0.0379 | 2 |
| Selumetinib | MMAC-SF | 0.0100 | uM | 72 | hr | 2566 | 79 | 0.7235 | 0.7588 | 0.0308 | 0.0379 | 3 |
| Selumetinib | MMAC-SF | 0.0100 | uM | 72 | hr | 3030 | 116 | 0.8477 | 0.7588 | 0.0383 | 0.0379 | 4 |