Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selumetinib | WM-115 | 0.0032 | uM | 72 | hr | 3342 | 93 | 1.0717 | 1.0349 | 0.0278 | 0.0278 | 4 |
| Selumetinib | WM-115 | 0.0100 | uM | 24 | hr | 660 | 31 | 1.2013 | 1.2724 | 0.0470 | 0.0509 | 1 |
| Selumetinib | WM-115 | 0.0100 | uM | 24 | hr | 610 | 26 | 1.1154 | 1.2724 | 0.0426 | 0.0509 | 2 |
| Selumetinib | WM-115 | 0.0100 | uM | 24 | hr | 832 | 43 | 1.5069 | 1.2724 | 0.0517 | 0.0509 | 3 |
| Selumetinib | WM-115 | 0.0100 | uM | 24 | hr | 707 | 44 | 1.2662 | 1.2724 | 0.0622 | 0.0509 | 4 |
| Selumetinib | WM-115 | 0.0100 | uM | 48 | hr | 1001 | 34 | 1.9523 | 1.3870 | 0.0340 | 0.0343 | 1 |
| Selumetinib | WM-115 | 0.0100 | uM | 48 | hr | 876 | 26 | 1.7161 | 1.3870 | 0.0297 | 0.0343 | 2 |
| Selumetinib | WM-115 | 0.0100 | uM | 48 | hr | 546 | 18 | 1.0660 | 1.3870 | 0.0330 | 0.0343 | 3 |
| Selumetinib | WM-115 | 0.0100 | uM | 48 | hr | 420 | 17 | 0.8136 | 1.3870 | 0.0405 | 0.0343 | 4 |
| Selumetinib | WM-115 | 0.0100 | uM | 72 | hr | 3098 | 84 | 0.9942 | 1.0695 | 0.0271 | 0.0270 | 1 |
| Selumetinib | WM-115 | 0.0100 | uM | 72 | hr | 3159 | 70 | 1.0190 | 1.0695 | 0.0222 | 0.0270 | 2 |
| Selumetinib | WM-115 | 0.0100 | uM | 72 | hr | 3337 | 107 | 1.0655 | 1.0695 | 0.0321 | 0.0270 | 3 |
| Selumetinib | WM-115 | 0.0100 | uM | 72 | hr | 3735 | 99 | 1.1994 | 1.0695 | 0.0265 | 0.0270 | 4 |
| Selumetinib | WM-115 | 0.0316 | uM | 24 | hr | 630 | 35 | 1.1364 | 1.3579 | 0.0556 | 0.0515 | 1 |
| Selumetinib | WM-115 | 0.0316 | uM | 24 | hr | 581 | 40 | 1.0332 | 1.3579 | 0.0688 | 0.0515 | 2 |
| Selumetinib | WM-115 | 0.0316 | uM | 24 | hr | 867 | 30 | 1.5985 | 1.3579 | 0.0346 | 0.0515 | 3 |
| Selumetinib | WM-115 | 0.0316 | uM | 24 | hr | 914 | 43 | 1.6635 | 1.3579 | 0.0470 | 0.0515 | 4 |
| Selumetinib | WM-115 | 0.0316 | uM | 48 | hr | 847 | 35 | 1.6393 | 1.3728 | 0.0413 | 0.0345 | 1 |
| Selumetinib | WM-115 | 0.0316 | uM | 48 | hr | 942 | 40 | 1.8210 | 1.3728 | 0.0425 | 0.0345 | 2 |
| Selumetinib | WM-115 | 0.0316 | uM | 48 | hr | 523 | 9 | 1.0377 | 1.3728 | 0.0172 | 0.0345 | 3 |
| Selumetinib | WM-115 | 0.0316 | uM | 48 | hr | 511 | 19 | 0.9933 | 1.3728 | 0.0372 | 0.0345 | 4 |
| Selumetinib | WM-115 | 0.0316 | uM | 72 | hr | 2666 | 98 | 0.8471 | 0.9176 | 0.0368 | 0.0324 | 1 |
| Selumetinib | WM-115 | 0.0316 | uM | 72 | hr | 2937 | 101 | 0.9355 | 0.9176 | 0.0344 | 0.0324 | 2 |
| Selumetinib | WM-115 | 0.0316 | uM | 72 | hr | 2829 | 79 | 0.9071 | 0.9176 | 0.0279 | 0.0324 | 3 |
| Selumetinib | WM-115 | 0.0316 | uM | 72 | hr | 3067 | 94 | 0.9807 | 0.9176 | 0.0306 | 0.0324 | 4 |