Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset - HMS LINCS Database

Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

Small molecules	Cells
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Small Molecule	Cell Line	Drug Concentration	Conc Unit	Time Point	Time Point Unit	Total Number of Cells (Nuclei)	Number of Apoptotic Cells	Relative Viability	Mean Relative Viability	Apoptosis Fraction	Mean Apoptosis Fraction	Replicate
Selumetinib	SKMEL28	1.0000	uM	24	hr							3
Selumetinib	SKMEL28	1.0000	uM	24	hr							4
Selumetinib	SKMEL28	1.0000	uM	48	hr	1664	87	0.9393	0.8520	0.0523	0.0573	1
Selumetinib	SKMEL28	1.0000	uM	48	hr	1511	93	0.8446	0.8520	0.0615	0.0573	2
Selumetinib	SKMEL28	1.0000	uM	48	hr	1456	84	0.8172	0.8520	0.0577	0.0573	3
Selumetinib	SKMEL28	1.0000	uM	48	hr	1438	83	0.8070	0.8520	0.0577	0.0573	4
Selumetinib	SKMEL28	1.0000	uM	72	hr	556	70	0.3646	0.4189	0.1259	0.1114	1
Selumetinib	SKMEL28	1.0000	uM	72	hr	719	77	0.4816	0.4189	0.1071	0.1114	2
Selumetinib	SKMEL28	1.0000	uM	72	hr	543	63	0.3601	0.4189	0.1160	0.1114	3
Selumetinib	SKMEL28	1.0000	uM	72	hr	693	67	0.4696	0.4189	0.0967	0.1114	4
Selumetinib	SKMEL28	3.1600	uM	24	hr							1
Selumetinib	SKMEL28	3.1600	uM	24	hr							2
Selumetinib	SKMEL28	3.1600	uM	24	hr							3
Selumetinib	SKMEL28	3.1600	uM	24	hr							4
Selumetinib	SKMEL28	3.1600	uM	48	hr	1237	130	0.6593	0.6044	0.1051	0.0991	1
Selumetinib	SKMEL28	3.1600	uM	48	hr	1089	119	0.5777	0.6044	0.1093	0.0991	2
Selumetinib	SKMEL28	3.1600	uM	48	hr	1070	87	0.5855	0.6044	0.0813	0.0991	3
Selumetinib	SKMEL28	3.1600	uM	48	hr	1111	112	0.5950	0.6044	0.1008	0.0991	4
Selumetinib	SKMEL28	3.1600	uM	72	hr	471	125	0.2595	0.3372	0.2654	0.2145	1
Selumetinib	SKMEL28	3.1600	uM	72	hr	623	143	0.3601	0.3372	0.2295	0.2145	2
Selumetinib	SKMEL28	3.1600	uM	72	hr	567	116	0.3383	0.3372	0.2046	0.2145	3
Selumetinib	SKMEL28	3.1600	uM	72	hr	619	98	0.3908	0.3372	0.1583	0.2145	4
Vemurafenib	SKMEL28	0.0032	uM	24	hr							1
Vemurafenib	SKMEL28	0.0032	uM	24	hr							2
Vemurafenib	SKMEL28	0.0032	uM	24	hr							3